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LNP Screening Array

Transform your liquid handler into an LNP screening platform.

Get Your Starter Kit

Submit the form and our team will follow up within 24 hours to help you get your Starter Kit.

= required
Parallel LNP Screening Array. A microplate-sized microfluidic device with eight sets of flow focusing micromixers at a 3:1 flow rate ratio.

Automate LNP screening from prep to formulation.

Run formulation on your existing automation, from sample prep to LNPs in one continuous workflow.

10x faster screening

Run formulations in parallel and generate LNPs in seconds.

1 automated workflow

Go from reagents to LNPs in a single automated sequence.

<50 µL dead volume

Screen more formulations while using less lipid and RNA.

0 new instruments

Run LNP screening on the liquid handler you already use.

A fast path to your first run.

Getting started doesn’t require a new workflow or weeks of setup. The Starter Kit helps your team increase screening throughput quickly, with protocol support and a clear path into recurring screening.

1

Get your Starter Kit.
Ships within one week, with everything in place for your first run.

2

Run your first screen.
Load your reagents, follow the protocol, and generate your first LNP formulations.

3

Scale your screening.
Once you establish fit, move into a recurring screening cadence.

Everything you need to start screening.

Starter Kit

A complete kit built to generate reproducible LNP data on your liquid handler.

LNP Screening Array

  • 8 staggered herringbone micromixers
  • 8 anti-backflow reservoirs
  • 16 pipette interfaces
  • SLAS microplate footprint

Automation protocol

  • Ready to run on your liquid handler

Deep-well plates

  • For reagent loading and LNP collection

Get Your Starter Kit

Submit the form and our team will follow up within 24 hours to help you get your Starter Kit.

= required
Top-down view of the Parallel Fluidics LNP Screening Array. A microplate-sized microfluidic device with eight sets of flow-focusing micromixers, all with a 3:1 flow rate ratio.

Each Starter Kit includes fluidic resistance ratios matched to your formulation goals and liquid handler.

  • 1:1

    Top-down view of the Parallel Fluidics LNP Screening Array. A microplate-sized microfluidic device with eight sets of flow-focusing micromixers, all with a 1:1 flow rate ratio.

  • 3:1

    Top-down view of the Parallel Fluidics LNP Screening Array. A microplate-sized microfluidic device with eight sets of flow-focusing micromixers, all with a 3:1 flow rate ratio.

  • 5:1

    Top-down view of the Parallel Fluidics LNP Screening Array. A microplate-sized microfluidic device with eight sets of flow-focusing micromixers, all with a 5:1 flow rate ratio.

  • 7:1

    Top-down view of the Parallel Fluidics LNP Screening Array. A microplate-sized microfluidic device with eight sets of flow-focusing micromixers, all with a 7:1 flow rate ratio.

Reproducible LNP screening data you can build on.

Particle size and PDI data generated on leading liquid handling platforms.*

≤100 nm
Mean particle size across tested configurations

≤0.2
Mean PDI across tested configurations

3.38%
Average size %CV across tested conditions

* Results shown are from characterized test conditions and may vary by lipid composition, cargo, and automation platform.

Screen more LNP formulations faster.

Parallel Fluidics LNP Screening Array. A microplate-sized microfluidic device with eight sets of flow-focusing micromixers, all with a 3:1 flow rate ratio.

Get your Starter Kit and run your first LNP screen this week.

Get Your Starter Kit

Submit the form and our team will follow up within 24 hours to help you get your Starter Kit.

= required

Questions about compatibility or setup? Talk to our applications team.

FAQ

No. The LNP Screening Array is a consumable. There is no instrument to buy or install, and no service contract to sign.

Yes. The Starter Kit is designed for standard liquid handling workflows, with automation protocol support for leading liquid handler platforms.

No. If your team runs standard sample prep protocols, they can run an LNP screen.

Starter Kits ship within one week. Most teams begin their first evaluation as soon as the kit arrives.

Yes. We offer onsite demos and evaluations in the Boston and Cambridge area, and can discuss options for other locations. You can book a demo here.

Each Starter Kit includes an LNP Screening Array, automation protocol support for your liquid handler, and input and output plates for reagent loading and sample collection.
  • 8 staggered herringbone micromixers for LNP formation
  • 8 1mL anti-backflow reservoirs that prevent reagent backflow during aspiration and dispense cycles
  • 16 pipette interfaces that connect standard pipette tips to the array
  • SLAS microplate footprint that fits standard liquid handler decks

Different pipetting technologies require different mixer geometries for optimized LNP formation. Positive liquid displacement systems use the 1:1 micromixer because the instrument can directly set individual channel flow rates. Air displacement and pressure-controlled platforms use 3:1, 5:1, or 7:1 micromixers because channel resistance is used to control flow ratios.

Most LNP tools require a dedicated instrument, proprietary cartridges, or a separate off-deck workflow. The LNP Screening Array runs directly on your liquid handler, enabling parallel screening and up to 10x faster throughput without a dedicated instrument.

The LNP Screening Array helps teams screen faster, reduce hands-on work, and expand discovery capacity on the liquid handler they already use.

Yes. Most teams are successful with the LNP Screening Array. If your application requires a custom configuration, contact us to discuss your requirements.